1
Individuals who have engaged in unprotected intercourse, particularly with new or multiple partners, should consider testing.
2
The appearance of sores, rashes (especially on the palms and soles), swollen lymph nodes, or flu-like symptoms may indicate an infection.
3
Expectant mothers are routinely screened to prevent complications related to congenital syphilis.
4
If a sexual partner has tested positive, immediate testing is necessary, regardless of symptom presence.